A 30-year-old male patient will begin a three-drug regimen to treat peptic ulcer disease. The regimen will consist of bismuth subsalicylate, tetracycline, and cimetidine [Tagamet]
The nurse will include which information when teaching this patient about this drug regimen? a. Black discoloration of the tongue and stools should be reported immediately.
b. Central nervous system depression and confusion are likely to occur.
c. Decreased libido, impotence, and gyne-comastia are reversible side effects.
d. Staining of the teeth may occur and is an indication for discontinuation of these drugs.
C
Cimetidine has antiandrogenic effects and can cause decreased libido, impotence, and gyneco-mastia. These effects are reversible. Black stools and discoloration of the tongue are side effects associated with bismuth but are not harmful. Central nervous system (CNS) depression and con-fusion are not likely. Staining of the teeth associated with tetracycline use occurs only in devel-oping teeth; it is a problem in children younger than 8 years and in pregnant woman because of this risk to the fetus.
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