Which of the following is a way in which follicular B cells can acquire antigen entering a lymph node via an afferent lymphatic?
A. Direct capture of whole antigen that directly enters the follicle by passing between sub-capsular sinus macrophages
B. Transfer of complement-bound antigen from surface receptors on sub-capsular sinus macrophages to B cells
C. Passage of antigen from sub-capsular sinus macrophages to follicular dendritic cells to B cells
D. Passage of antigen from DCs that reside near HEVs to B cells
E. All of the above are possible.
E
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Indicate whether the statement is true or false.