Jan has a history of miscarriage in the first trimester. Her physician thinks that her problem might be hormonal. What hormones could be implicated in failing to maintain the pregnancy during the first trimester and why?


Ans:

The hormones that could be implicated in failing to maintain a pregnancy during the first trimester are progesterone and PIBF (Progesterone-induced blocking factor). This is because low levels of progesterone will cause the uterine lining to shed and cause a period to start. If levels of progesterone are low, then if a healthy fertilized egg has attached to the wall, a miscarriage will occur if this shedding is triggered.

Anatomy & Physiology

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