You are a scientist at a pharmaceutical company. You know that treating Parkinson's disease patients with dopamine has been ineffective in the past, however, your company has recently developed a method to modify drugs that can help them cross the blood-brain barrier. If you modified dopamine in this way, would it make dopamine treatment of Parkinson's more effective?

A. No, because injecting dopamine only makes the substantia nigra down-regulate its own production of dopamine.
B. No, because dopamine will be broken down in the body before reaching the brain.
C. Yes, a central issue with dopamine treatment is that dopamine cannot cross the blood-brain barrier.
D. No, because acetylcholine is the main neurotransmitter that is deficient.


Answer: C

Anatomy & Physiology

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