A patient is admitted to the intensive care unit for treatment of shock. The prescriber orders isoproterenol [Isuprel]. The nurse expects this drug to increase tissue perfusion in this patient by activating:
a. alpha1 receptors to cause vasoconstriction.
b. alpha1 receptors to increase blood pressure.
c. beta1 receptors to cause a positive ino-tropic effect.
d. beta2 receptors to cause bronchodilation.
C
Isoproterenol is used for shock because of its actions on beta1 receptors in the heart. It has a posi-tive inotropic effect, which improves cardiac output and thus increases tissue perfusion. Isopro-terenol does not affect alpha1 receptors. Although it activates beta2 receptors to cause bronchodi-lation, this is not indicated for the treatment of shock.
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