What leukemia is most likely in a patient whose bone marrow is composed of predominantly large, multinucleated, dysplastic erythroid precursors?
a. Acute myelomonocytic leukemia
b. Acute megakaryocytic leukemia
c. Acute erythroleukemia
d. Acute myeloid leukemia with minimal maturation
ANS: C
The bone marrow erythroid precursors display significant dysplastic features, including multinucleation, megaloblastoid asynchrony, and vacuolization, in acute erythroleukemia. Abnormal megakaryocytes may also be present.
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