A patient who is taking colchicine for gout is in the clinic 1 week after beginning the medication. The patient reports decreased appetite and nausea. The primary care NP should:
a. suspect worsening of gouty arthritis.
b. order vitamin B12 levels to assess for vitamin deficiency.
c. discontinue the colchicine for 48 hours until symptoms subside.
d. reassure the patient that these are common, temporary side effects.
C
Colchicine toxicity causes nausea, vomiting, and anorexia. When toxicity is suspected, the medication should be temporarily discontinued and restarted after symptoms subside.
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