Order: Polymixin B sulfate 25,000 units/kg/d in four equally divided doses IM. The label on the vial reads 500,000 units. The manufacturer recommends diluting 500,000 units with 5 ml of sterile water
How many milliliters will you prepare for a single dose if the patient weighs 150 pounds? 1. 4.3 mL
2. 7.5 mL
3. 68.2 mL
4. 0.85 mL
1
Global Rationale: 68.2 kg × 25,000 units/kg = 1,705,000 units ÷ 4 = 426,250 units = 4.3 mL.
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