Explain how professional antigen-presenting cells optimize antigen presentation to T cells despite the relatively limited capacity of any particular MHC molecule to bind different pathogen-derived peptides

What will be an ideal response?


Professional antigen-presenting cells express several different types of MHC molecule on the cell surface, and each type has the potential to bind to different peptides. In addition, MHC molecules are highly polymorphic, so that most individuals are heterozygous and encode different allelic forms at each gene locus. The variety of peptides that can bind to these MHC molecules is therefore increased.

Health & Biomechanics

You might also like to view...

The function of the incisors is:

A) to cut food. B) to tear food. C) to grind food. D) all of the above.

Health & Biomechanics

Larry learned that his stroke had been caused by a blood clot in an artery in his brain. What caused Larry's stroke?

a. cerebral thrombosis b. aneurysm c. low blood pressure d. hypertension e. plaque

Health & Biomechanics

People experiencing chronic, severe stress or who have persistent emotional problems have a higher incidence of cancer than those who don't suffer from these conditions

Indicate whether the statement is true or false

Health & Biomechanics

Endotracheal: __________

Fill in the blank(s) with correct word

Health & Biomechanics