A patient with hyperlipidemia has a new order for colesevelam (Welchol). Which nursing action is most appropriate when giving the medication?
a. Have the patient take this medication with an aspirin.
b. Administer the medication at the patient's usual bedtime.
c. Have the patient take the colesevelam with a sip of water.
d. Give the patient's other medications 2 hours after the colesevelam.
ANS: D
The bile acid sequestrants interfere with the absorption of many other drugs, and giving other medications at the same time should be avoided. Taking an aspirin concurrently with the colesevelam may increase the incidence of gastrointestinal side effects such as heartburn. An increased fluid intake is encouraged for patients taking the bile acid sequestrants to reduce the risk for constipation. For maximum effect, colesevelam should be administered with meals.
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