A patient of Jewish heritage is experiencing body aches and fatigue. The nurse notes that the patient's skin appears pale and yellow-tinged. What nutritional health problem should the nurse suspect is occurring in this patient?
1. Tangier disease
2. hypercholesterolemia
3. Gaucher disease
4. Lynch Syndrome
Correct Answer: 3
This patient's findings are most consistent with Gaucher disease, which is more common in descendants of Jewish people from Eastern Europe. The disorder results in lack of an enzyme to break down fats, which accumulate in the liver, spleen, and bone marrow, causing pain, fatigue, jaundice, bone damage, anemia, and even death. Tangier disease is a disease of cholesterol transport characterized by orange tonsils, very low levels of high-density lipoprotein, and an enlarged liver and spleen. These findings are not characteristic of hypercholesterolemia. Lynch syndrome is a type of inherited cancer of the GI system, especially the colon and rectum. Colon polyps occur at an early age and are more likely to become malignant.
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