A young adult male client presents to the orthopedic clinic complaining of "stiffening of the spine." The health care provider orders some diagnostic lab work. Which lab result leads the health care worker to diagnose ankylosing spondylitis?
A) Elevated serum calcium level of 15.1 mg/dL
B) Severe decrease in red blood cells associated with decreased iron levels
C) Presence of HLA-B27 allele marker
D) Elevated serum uric acid level
Ans: C
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The HLA-B27 antigen remains one of the best-known examples of an association between a disease and a hereditary marker; approximately 90% of those with ankylosing spondylitis possess the HLA-B27 antigen. Primary gout is often caused by an inborn error in metabolism and is characterized primarily by hyperuricemia and gout. The person also may have a mild normocytic normochromic anemia but not iron deficiency anemia.
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