A patient is admitted to a long-term psychiatric setting. The MAOI medication previously prescribed is discontinued by the physician. New orders are obtained to initiate imipramine therapy

The nurse will provide the first dose of imipramine to the patient _____ the MAOI drug.
a. immediately following the last dose of
b. in 1 week following the last dose of
c. in 14 days following the last dose of
d. before discontinuing


ANS: C
MAOIs and TCAs, especially imipramine and desipramine, should not be administered concurrently. It is recommended that at least 14 days lapse between discontinuing an MAOI and starting SSRI/SNRI therapy.

Nursing

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