Which of the following statements about transcriptional regulators is false?
(a) Transcriptional regulators usually interact with the sugar-phosphate backbone on the outside of the double helix to determine where to bind on the DNA helix
(b) Transcriptional regulators will form hydrogen bonds, ionic bonds, and hydrophobic interactions with DNA
(c) The DNA-binding motifs of transcriptional regulators usually bind in the major groove of the DNA helix
(d) The binding of transcriptional regulators generally does not disrupt the hydrogen bonds that hold the double helix together
Ans: (a) Transcriptional regulators usually interact with the sugar-phosphate backbone on the outside of the double helix to determine where to bind on the DNA helix
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