A client has been diagnosed with myasthenia gravis and is experiencing severe muscle weakness. The nurse teaches the client that these symptoms are occurring because of the destruction of what receptor?
1. Nicotinic (cholinergic) receptors found in skeletal muscles
2. Norepinephrine (adrenergic) receptors found in skeletal muscle
3. Muscarinic (cholinergic) receptors found in smooth muscle
4. Norepinephrine (adrenergic) receptors found in smooth muscle
1
Rationale 1:Nicotinic (cholinergic) receptors found in skeletal muscles is correct because myasthenia gravis is a disease characterized by destruction of nicotinic (cholinergic) receptors on skeletal muscles.
Rationale 2:Norepinephrine (adrenergic) receptors found in skeletal muscle is incorrect because adrenergic receptors constrict blood vessels, dilate pupils, inhibit release of norepinephrine, increase heart rate and force of contractions, release renin, and inhibit smooth muscle.
Rationale 3:Muscarinic (cholinergic) receptors found in smooth muscle is incorrect because muscarinic (cholinergic) receptors stimulate smooth muscle and gland secretion, and decrease the force of contraction and rate of the heart.
Rationale 4:Norepinephrine (adrenergic) receptors found in smooth muscle is incorrect because adrenergic receptors constrict blood vessels, dilate pupils, inhibit release of norepinephrine, increase heart rate and force of contractions, release renin, and inhibit smooth muscle.
Global Rationale: Nicotinic (cholinergic) receptors found in skeletal muscles is correct because myasthenia gravis is a disease characterized by destruction of nicotinic (cholinergic) receptors on skeletal muscles. Norepinephrine (adrenergic) receptors found in skeletal muscle is incorrect because adrenergic receptors constrict blood vessels, dilate pupils, inhibit release of norepinephrine, increase heart rate and force of contractions, release renin, and inhibit smooth muscle. Muscarinic (cholinergic) receptors found in smooth muscle is incorrect because muscarinic (cholinergic) receptors stimulate smooth muscle and gland secretion, and decrease the force of contraction and rate of the heart. Norepinephrine (adrenergic) receptors found in smooth muscle is incorrect because adrenergic receptors constrict blood vessels, dilate pupils, inhibit release of norepinephrine, increase heart rate and force of contractions, release renin, and inhibit smooth muscle.
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