When the replication machinery encounters a single-strand break, the replication fork collapses resulting in a double-strand break. Which of the following would be the fourth step in repairing this damage?

A. The 3' single-strand overhang invades the intact portion of the chromosome, pairs with its complementary strand, and displaces the other.
B. Once the strand invasion is complete, branched migration occurs.
C. The broken ends are processed, with the 5' ending strand selectively degraded to create 3' overhangs.
D. Branch migration creates Holliday intermediates that are resolved by the enzyme resolvase.
E. Resolution of the Holliday intermediate is followed by ligation and replication is restarted.


D

Biology & Microbiology

You might also like to view...

You are mapping the location of two genes in Drosophila, listless l and blind b. (l+ l+ b+ b+) and (l+ l- b+ b-) flies are normal, but ( l- l- b- b-) flies don't move around very much and cannot detect the location of a light source. You perform a testcross and get the following results:

listless, sighted 100 listless, blind 400 normal activity, sighted 400 normal activity, blind 100 What is the distance between these two genes on the chromosome? A. They are on different chromosomes. B. They are 10 map units apart. C. They are 20 map units apart. D. They are 40 map units apart. E. They are 80 map units apart.

Biology & Microbiology

The ____ is a Gram-negative bacterium

a. Clostridium b. Staphylococcus c. Streptococcus d. Salmonella e. Lactobacillus

Biology & Microbiology

The most common GMOs are

a. protists and plants b. fungi c. animals d. bacteria and fungi e. plants

Biology & Microbiology

The axial skeleton includes all EXCEPT which of the

following? a. skull b. ribs c. pectoral girdle d. sternum e. vertebral column

Biology & Microbiology