The Y chromosome is present in only one copy in males, and therefore most of the genes it contains are effectively haploid
Although there is recombination between the pseudoautosomal regions of the X and Y, there is not a homologous section for large parts of the Y chromosome. How are the male-specific genes prevented from accumulating mutations and becoming nonfunctional?
What will be an ideal response?
Ans: The 60 or so male-specific genes are present in multiple copies (ampliconic segments) on the Y chromosome and undergo recombination within these regions to maintain active genes via a process called gene conversion. Through recombination, inactivated genes are replaced from the pool of active genes in these segments.
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