What explanation is generally given for lethality of monosomic individuals?

A) The gametes of monosomic individuals cannot undergo meiosis, and this is lethal.
B) Monosomy may unmask recessive lethals that are tolerated in heterozygotes carrying the wild-type allele.
C) Cells count the number of chromosomes they have and will undergo apoptosis when the chromosome number is incorrect.
D) The loss of a single chromosome is not generally lethal, unless the individual is inbred.
E) Monosomic chromosomes cannot undergo mitosis correctly.


Answer: B

Biology & Microbiology

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