The nurse prepares to administer a drug that binds highly with protein to a 2-month-old infant and notes that the dosage is significantly lower than the recommended adult dose. The nurse should:
1. recognize that a dose reduction is necessary because the decreased amount of albumin in the infant's blood increases the concentration level of free drug.
2. question the order because protein binding decreases the concentration level of free drug.
3. expect an increased dose to accommodate the lower levels of circulating drug resulting from protein binding.
4. expect a decreased dose in order to further prevent toxicity from high levels of free drug.
Correct Answer: 1
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