DNA replication can stall as a consequence of the replication machinery encountering hairpin DNA structures that can form due to inverted repeats and palindromic sequences

When DNA replication stalls, double-strand breaks in the DNA can occur, causing severe genetic and cellular consequences. Both Werner syndrome (premature onset of age-related phenotypes and cancer) and Bloom syndrome (cancer) are the result of mutations in helicase, an enzyme that unwinds hairpin structures. Helicase most likely breaks which type of bonds in a hairpin?

A. glycosidic
B. phosphodiester
C. hydrogen
D. peptide
E. covalent


C

Biology & Microbiology

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One of the most pathogenic hemorrhagic fever viruses belongs to the _________ family

a. Filoviridae b. Flaviviridae c. Papovaviridae d. Picornaviridae

Biology & Microbiology

This phylum of nonvascular plants has about 6000 known living species. It includes the genus

Marchantia, whose members can reproduce asexually via cups called gemmae.

a. Hepatophyta b. Pterophyta c. Bryophyta d. Lycophyta e. Anthocerophyta

Biology & Microbiology

In sponges, spicules are secreted by amoeboid cells

____________________ Indicate whether the statement is true or false.

Biology & Microbiology

What is the animal in the accompanying figure?

a. mosasaur b. plesiosaur c. pterosaur d. thecodont e. ichthyosaur

Biology & Microbiology