Which medication should the nurse anticipate to be prescribed for a client with asthma and hypertension?
1. Metoprolol (Lopressor)
2. Propranolol (Inderal)
3. Sotalol (Betapace)
4. Nadolol (Corgard)
Correct Answer: 1
Rationale 1: Metoprolol is a selective beta1-adrenergic blocker that blocks beta1 receptors in the cardiac tissue only. Since it does not affect the receptors in the lungs, there is less possibility of bronchospasm.
Rationale 2: Propranolol is a nonselective beta-adrenergic blocker; hence, it is contraindicated in asthma or COPD, since it can cause bronchospasm by its action on the beta2 receptors in the lungs.
Rationale 3: Sotalol is a nonselective beta-adrenergic blocker, so it is contraindicated for asthma or COPD, since it can cause bronchospasm by its action on the beta2 receptors in the lungs.
Rationale 4: Nadolol is a nonselective beta-adrenergic blocker, so it is contraindicated in asthma or COPD, since it can cause bronchospasm by its action on the beta2 receptors in the lungs.
Global Rationale: Metoprolol is a selective beta1-adrenergic blocker that blocks beta1 receptors in the cardiac tissue only. Since it does not affect the receptors in the lungs, there is less possibility of bronchospasm. Propranolol, sotaol, and nadolol are all nonselective beta-adrenergic blockers. They are contraindicated in asthma or COPD, since they can cause bronchospasm by their action on the beta2 receptors in the lungs.
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