From the following list, select the items associated with prostaglandins
a. pain.
b. inflammation.
c. reduces gastric acid.
d. reduces uterine contractions.
e. fever
f. increased renal blood flow
g. increased blood pressure
a, e,f,g. Prostaglandins are found in the stomach, kidneys, uterus, lung, and vascular smooth muscle.
13.a, b,c,d,e,f. Once released, prostaglandins are metabolized rapidly. The biologic effects of prostaglandins include:
• PGE2, which has potent inflammatory properties and is elevated in inflammatory periodontal diseases (periodontitis).
• Production of gastric mucus and reduction of the production of gastric acid (protective effects).
• Uterine contractions during labor.
• PGI2 (prostacyclin) is released from blood vessels and inhibits platelet (clot) formation.
• Bronchodilation (PGE2 and PGI2) and bronchoconstriction (PGF2a).
• Increased renal blood flow.
• Reduction in blood pressure.
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