What is the fate of centrocytes in which somatic hypermutation has resulted in high-affinity receptors for antigen? (Select all that apply.)
a. They die by apoptosis.
b. They express Bcl-xL.
c. They process antigen and present it to TFH cells.
d. CD40 on the centrocyte engages with CD40 ligand on TFH cells.
e. They undergo phagocytosis by tingible body macrophages.
b, c, d
Health & Biomechanics
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