Mismatch repair targets improperly paired nucleotides. In prokaryotes, the incorrect member of an abnormal base pair can be differentiated from the correct member because
A) the incorrect member has undergone a hydroxylation reaction.
B) newly synthesized DNA contains uracil.
C) the incorrect member doesn't match the surrounding bases.
D) the original strand of DNA contains methylated bases while newly synthesized DNA does not; thus the correct member is in the methylated strand.
E) the correct member has been deaminated.
Answer: D
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