Which information should the nurse include in a teaching plan about cortisol for a patient who is HIV-positive?

A) Chronically high levels of cortisol accelerate immune decline.
B) Cortisol levels that are lowest in the morning boost the immune response.
C) A flattened cortisol circadian pattern indicates a healthy immune system.
D) Low cortisol levels are associated with the development of AIDS.


A) Chronically high levels of cortisol accelerate immune decline.

Explanation: A) Elevated cortisol levels predict accelerated immune decline and development of AIDS in individuals who are HIV-positive.
B) HIV-infected individuals display physiologic changes that are consistent with chronic elevations of resting levels of cortisol, as evidenced by muted cortisol responsivity (due to downregulated receptors), and a flattened cortisol circadian rhythm. Cortisol is secreted in a circadian pattern, with high levels in the morning that decrease to low levels at bedtime. Elevated cortisol levels predict accelerated immune decline.
C) HIV-infected individuals display physiologic changes that are consistent with chronic elevations of resting levels of cortisol, as evidenced by muted cortisol responsivity (due to downregulated receptors), and a flattened cortisol circadian rhythm. Cortisol is secreted in a circadian pattern, with high levels in the morning that decrease to low levels at bedtime. Elevated cortisol levels predict accelerated immune decline.
D) Elevated cortisol levels predict accelerated immune decline and development of AIDS in individuals who are HIV-positive.

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