Summarize two pathways to colon cancer

What will be an ideal response?


The first pathway to FAP colon cancer begins with a mutation in the APC gene. This mutation causes formation of large numbers of noncancerous polyps that slowly progress to cancer. The second pathway to HNPCC colon cancer begins with a mutation in a DNA repair gene. Polyps form slowly but mutations accumulate rapidly, making it almost certain that at least one polyp will progress to colon cancer.

Biology & Microbiology

You might also like to view...

Plants exude ____ from roots to stimulate the growth of soil fungi

a. strigolactones b. cytokinins c. ethylene d. auxins e. jasmonates

Biology & Microbiology

Match the symbol on the left with its description on the right

A) y-intercept of a Lineweaver–Burk plot B) turnover number C) Michaelis–Menten constant D) maximum velocity E) substrate concentration F) slope of a Michaelis–Menten plot 1) Km 2) kcat 3) Vmax 4) [S] 5) Km/Vmax 6) 1/Vmax

Biology & Microbiology

A temporary oxygen deficit during strenuous exercise causes a muscle to

A) synthesize muscle proteins in response to steroid hormone stimulation. B) synthesize glycogen. C) ferment pyruvate to lactate. D) switch to aerobic glycolysis. E) synthesize more NAD+.

Biology & Microbiology

If yeast cells are incubated under anaerobic conditions, the pyruvate they produce is converted to lactate

__________________ Indicate whether the statement is true or false.

Biology & Microbiology