A patient is being treated with long-term methotrexate (Trexall) for severe psoriasis. Which laboratory result or results are most important for the nurse to monitor? (Select all that apply.)
a. Potassium level
b. Complete blood counts (CBC)
c. Liver function studies
d. Renal function studies
e. Serum sodium level
ANS: B, C
The nurse should monitor the patient's CBC and liver function studies, because methotrexate is absorbed systemically and may cause anemia, leukopenia, thrombocytopenia, and hepatic dysfunction.
Nothing indicates that potassium, sodium, or renal function is affected by the use of methotrexate.
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