Name the cells of the neutrophil lineage in order from earliest morphologically recognizable cell to most mature cell and include one unique morphologic characteristic of each cell

Question

What will be an ideal response?

Answer 1

Answer: Myeloblast, promyelocyte, myelocyte, metamyelocyte, band, neutrophil
Myeloblast: There is a small amount of cytoplasm that is agranular, staining from deep blue to a lighter blue.
Promyelocyte: The basophilic cytoplasm is similar to that of the myeloblast but is differentiated by the presence of prominent reddish-purple primary granules.
Myelocyte: The nucleus can be round, oval, slightly flattened on one side, or slightly indented. The hallmark for the myelocyte stage is the appearance of specific or secondary granules and can be referred to as the "dawn of neutrophilia."
Metamyelocyte: Nuclear indentation that gives the nucleus a kidney bean shape can be a characteristic that differentiates a metamyelocyte from a myelocyte, but nuclear shape is variable and is not the most reliable identifying feature. The nuclear chromatin is coarse and clumped and stains dark purple. The ratio of secondary to primary granules is ~2:1
Band: Nuclear indentation gives the nucleus a horseshoe shape, and the chromatin is condensed. The band neutrophil is the first stage that normally is found in the peripheral blood.
Segmented neutrophil: Segmented nucleus with two or more lobes connected by a thin nuclear filament. The chromatin is condensed and stains a deep purple black.