The multiple marker screen is used to assess the fetus for which condition?

a. Down syndrome
b. Diaphragmatic hernia
c. Congenital cardiac abnormality
d. Anencephaly


A
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A The maternal serum level of alpha-fetoprotein is used to screen for Trisomy 18
or 21, neural tube defects, and other chromosomal anomalies.
B The quadruple marker test does not detect this fetal anomaly. Additional testing,
such as ultrasonography would be required to diagnose diaphragmatic hernia.
C Congenital cardiac abnormality would most likely be identified during an
ultrasound examination.
D The quadruple marker test would not detect anencephaly.

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