Which of the following describes processes by which self-reactive lymphocytes are rendered incapable of mounting an autoimmune response? (Select all that apply.)

a. sequestration of autoantigens in immunologically privileged sites
b. induction of anergy in peripheral compartments
c. positive selection of autoimmune T lymphocytes in secondary lymphoid tissues
d. negative selection of T lymphocytes in the thymus
e. suppression by regulatory T cells
f. negative selection of B lymphocytes in the bone marrow
g. expression of AIRE in the bone marrow
h. induction of alloreactive responses it the thymus
i. somatic hypermutation to an alternative antigen specificity
j. apoptosis in primary lymphoid tissue
k. deprivation of T-cell help.


a, b, d, e, f, j, k

Health & Biomechanics

You might also like to view...

Which of the following statements is true about heart disease in women?

A. Heart attack is the leading cause of death of women in the United States. B. Women under 50 years of age are twice as likely to die from heart attack as men under 50. C. 38% of women who survive a heart attack die within the first year compared to 21% of men. D. all of these choices

Health & Biomechanics

The combining form steth/o- means "listening."

Indicate whether the statement is true or false

Health & Biomechanics

Match the combining form for dermat/o.

A. Hair B. Black C. Fungus D. Skin

Health & Biomechanics

Discuss changes in appearance caused by smoking

Health & Biomechanics