Which laboratory blood test result for a patient taking trimethoprim/sulfamethoxazole (Septra) does the nurse report immediately to the prescriber?
a. Red blood cells (RBCs) 2.2 million/mm3
b. International normalized ratio (INR) 1.6
c. White blood cells (WBCs) 6,000/mm3
d. Sodium 134 mEq/L
A
Trimethoprim/sulfamethoxazole is a combination drug composed of two metabolism inhibitors. One of the most serious adverse effects of the metabolism inhibitors is suppression of bone mar-row cell division, leading to fewer red blood cells and anemia. This patient's RBC level is only about half of normal.
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