The nurse cares for a client with metabolic acidosis and hyperphosphatemia. What pathophysiological process does the nurse recognize is the reason for the client's phosphate abnormality?
A) Depression of glycolysis
B) Ionized calcium is decreased
C) Hydrogen ions move out of the cells
D) Positive and negative ions enter the cells
A) Depression of glycolysis
Explanation: A) In acidosis, there is an increase in serum phosphate because glycolysis is depressed during acidosis, and there is decreased utilization of phosphate in metabolic reactions.
B) Ionized calcium level is increased in acidosis and decreased in alkalosis.
C) In acidosis, hydrogen ions enter the cells and do not move out of the cells. In acidosis, some of the excess hydrogen ions enter the cells in exchange for the movement of potassium ions out of the cell.
D) In acidosis, there is an increase in serum phosphate because glycolysis is depressed during acidosis, and there is decreased utilization of phosphate in metabolic reactions. Ionized calcium level is increased in acidosis and decreased in alkalosis. In acidosis, Hydrogen enters the cells and does not move out of the cells. In acidosis, some of the excess of the excess hydrogen ions enter the cells in exchange for the movement of potassium ions out of the cell.
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