Which nursing assessment confirms that the angiotensin II receptor blocker (ARB) that a patient is taking is effective?
a. Weight loss of more than 2 pounds/week
b. LDL cholesterol levels have decreased.
c. Urinary output is increased.
d. Blood pressure has decreased.
ANS: D
The primary therapeutic outcome expected from angiotensin II receptor antagonists is reduction of blood pressure to within a normal range. Angiotensin II receptor antagonists bind angiotensin II receptor sites in the vascular smooth muscle, brain, heart, kidneys, and adrenal gland. The blood pressure-elevating (vasoconstricting) and sodium-retaining effects of angiotensin II are thus blocked. Weight loss, although advisable for treatment of hypertension, is not affected by ARBs. ARBs do not affect cholesterol levels. Urine output is not affected by ARBs.
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