Which of the following nucleoside reverse transcriptase inhibitors reduces the risk of perinatal human immunodeficiency virus (HIV) transmission?
a. Didanosine (Videx)
b. Lamivudine (Epivir)
c. Zalcitabine (Hivid)
d. Zidovudine (Retrovir)
ANS: D
To date, the only drugs with a demonstrated ability to reduce the risk of perinatal HIV transmis-sion are zidovudine and nevirapine. Zidovudine is effective in reducing perinatal HIV transmis-sion regardless of maternal viral load.
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