A nurse is teaching a group of nursing students about antibodies. The nurse correctly explains that which type of response is triggered when antigens bind to antibodies on mast cells or basophils?
a. Acquired immune response
b. Autoimmune response
c. Hypersensitivity reaction
d. Transplant rejection
ANS: C
When antigens bind to antibodies on mast cells and basophils, chemical mediators of hypersensitivity reactions are released. Although hypersensitivity is an acquired response, mast cells and basophils do not play a role in other acquired responses. An autoimmune response occurs when the immune system fails to discriminate between self and nonself. Transplant rejection occurs when the MHC molecules of the donor are different from those of the patient.
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