Jose is brought to the emergency room complaining of a burning sensation in his chest, increased salivation, and difficulty in swallowing. He is having difficulty breathing and feels the presence of a "lump in his throat." The diagnosis is gastroesophageal reflux disease. Explain.

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Gastroesophageal reflux disease is a disorder in which the rate of reflux is greater than in normal individuals and causes clinical symptoms and/or histological changes. Reflux and regurgitation may result in aspiration of gastric contents into the air passages, causing respiratory distress such as hoarseness, asthma, and pneumonia. The sensation of a lump in his throat may be due to esophageal sphincter pressure.

Anatomy & Physiology

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Anatomy & Physiology