Predict the effect on net filtration pressure if capsular hydrostatic pressure (CHP) was increased above normal
What will be an ideal response?
Capsular hydrostatic pressure (CHP) opposes filtration. This pressure is created by filtrate in the capsular space and typically contributes only 10 mm Hg to net filtration pressure (NFP), summarized by this equation: net filtration pressure = GHP - (GCOP + CHP). If CHP was higher than normal, the overall net filtration pressure would be reduced as filtration would be opposed. Thus, less filtrate would be made without the influence of regulatory mechanisms.
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