A number of mutations have been described in G proteins that have profound effects on their activity. For example, some mutations greatly increase the affinity of the G protein for GDP making it very difficult to be exchanged for GTP

Other mutations prevent the hydrolysis of
GTP to GDP.
Which of the following scenarios would still result in a proliferation signal via the kinase
cascade in the absence of ligand binding to its receptor tyrosine kinase?
A. A continuously active receptor and an
inactive Map kinase pathway
B. A Ras molecule that has no GTPase
activity
C. A continuously inactive MAP kinase
pathway and an inactive Ras
D. A continuously active Ras and an inactive
MAP kinase pathway
E. A continuously activated receptor in the
absence of ligand


B

Biology & Microbiology

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Apical meristems of dicots are at the tips of stems. Apical meristems of grasses are at ground level or slightly below, concealed by the leaves. The leaves also have an intercalary meristem at their bases

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