A nursing instructor is describing the different categories of antiretroviral agents used in treatment for HIV infection
The instructor determines that the teaching was successful when the students identify which category as affecting an enzyme so that new viral particles cannot mature?
A) Protease inhibitors
B) Reverse transcriptase inhibitors
C) Nonnucleoside reverse transcriptase inhibitors
D) Integrase inhibitors
Ans: A
Feedback:
Protease inhibitors block the protease enzyme so the new viral particles cannot mature.
Reverse transcriptase inhibitors block the reverse transcriptase enzyme so the HIV material cannot change into DNA in the new cell, preventing new HIV copies from being created. Nonnucleoside reverse transcriptase inhibitors latch on to the reverse transcriptase molecule to block the ability to make viral DNA. Integrase inhibitors prevent enzymes from inserting HIV genetic material into the cell's DNA.
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