Which condition would trigger the release of natriuretic peptide (NP)?
A. Hypovolemia with interstitial edema formation
B. Hypervolemia with increased venous return
C. Hypernatremia secondary to dehydration
D. Hyperkalemia secondary to trauma
B
Natriuretic peptide (both the A and B forms) is triggered by an increased venous return stret-ching the right atrial cells. Hypervolemia would cause such a situation. The result of increasing NP release is increased urinary excretion of sodium and water.
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