A patient who has been prescribed sertraline (Zoloft) reports to the nurse that she uses St. John's Wort. What danger does the nurse recognize?
1. Tardive dyskinesia
2. Serotonin syndrome
3. Stevens-Johnson rash
4. Anaphylactic reaction
Answer: 2
Explanation: Serotonin syndrome, a sometimes fatal condition, typically occurs when two or more medications that increase serotonin levels are used concurrently. St.John's Wort and Zoloft are two such substances. An anaphylactic reaction is a severe, whole-body allergic response to a medication. Stevens-Johnson rash is a severe hypersensitivity reaction to a medication or infection. Tardive dyskenesia is a condition characterized by extrapyramidal symptoms that result from certain anti-psychotic medications.
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