Which statements are true regarding the narrow chemical safety margin that infants demonstrate?

a. The immaturity of tubules may diminish the response to antidiuretic hormone (ADH).
b. An immature tubular transport capacity impairs the excretion of potassium.
c. An immature tubular transport capacity impairs the reabsorption of bicarbonate.
d. The immaturity of tubules may diminish the response to aldosterone.
e. The safety margin begins to expand after 2 years of age.


Answer:
a. The immaturity of tubules may diminish the response to antidiuretic hormone (ADH).
b. An immature tubular transport capacity impairs the excretion of potassium.
c. An immature tubular transport capacity impairs the reabsorption of bicarbonate.
e. The safety margin begins to expand after 2 years of age.

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