The mouse 'Groomer' gene is expressed in the brain and tongue. In the brain, the Groomer gene makes a mature mRNA that includes exons 1, 3, 4, and 5. In the tongue, the Groomer gene makes a mature mRNA that includes exons 1, 2, 4, and 5. Which one of the following could reasonably explain these observations?
a. the Groomer pre-mRNA lacks a 5' cap in one of the tissues
b. the Groomer pre-mRNA lacks a 3' poly(A) tail in one of the tissues
c. the translation start codon in the Groomer gene has been mutated in one of the tissues
d. exons in the Groomer pre-mRNA are alternatively spliced in the brain and tongue
Answer: d. exons in the Groomer pre-mRNA are alternatively spliced in the brain and tongue
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