All of the following are true of the classical pathway of complement activation except __________.
A) activated C1 activates C2 and C4
B) C3 is the first component to be activated
C) C5b joins C6, C7, C8, and C9 to form the membrane attack complex
D) C1 is activated by an antigen-antibody complex
E) activated C2a and C4b activate C3
Answer: B) C3 is the first component to be activated
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