In regard to killer-cell immunoglobulin-like receptors (KIRs) indicate which of the following statements is true (T) or false (F)
___ a. KIRs have a broader range of specificity for HLA class I compared with CD94:NKG2A.
___ b. KIRs are activating receptors of NK cells and stimulate the release of perforin and granzyme.
___ c. KIRs bind to monomorphic determinants on HLA-A, -B, and -C molecules.
___ d. All HLA-C allotypes are suitable ligands for KIRs.
___ e. KIRs are encoded in the leukocyte receptor complex (LRC) on chromosome 19.
___ f. MIC-A and MIC-B are suitable ligands for KIRs.
a—F; b—F; c—F; d—T; e—T; f—F
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