In untreated type 1 diabetes mellitus (insulin-dependent diabetes mellitus), acidosis occurs because:

A. dehydration concentrates the blood so even though H+ production is normal, its concentration is high.
B. kidney failure results in a decreased ability to excrete the normal amount of H+.
C. excess plasma glucose is taken up by the liver and converted to fatty acids.
D. insulin levels are extremely high, and insulin is an acidic protein hormone.
E. excessive lipolysis results in increased plasma fatty acid levels, which the liver converts to acidic ketones.


E

Anatomy & Physiology

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