A child has been receiving chloramphenicol for a Neisseria meningitidis central nervous system (CNS) infection. The nurse administers the dose and subsequently notes that the child has vo-mited and appears dusky and gray in color
The child's abdomen is distended. What will the nurse do? a. Contact the provider for an order to obtain a chloramphenicol level.
b. Notify the provider that the child's me-ningitis is worsening.
c. Recognize this as initial signs of a C. dif-ficile infection.
d. Stop the infusion immediately and notify the provider.
D
Gray syndrome is a potentially fatal toxicity associated with chloramphenicol use. When symp-toms occur, the drug should be stopped immediately. Lower chloramphenicol levels may prevent gray syndrome, but lowering the dose will not stop symptoms once they have appeared. These are not signs of worsening meningitis or a C. difficile infection.
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