When explaining to a patient why his prostate is enlarging, the nurse will mention that which of the following hormones may contribute to the prostatic hyperplasia? Select all that apply
A)
Glucocorticoids
B)
Testosterone
C)
Dihydrotestosterone
D)
Estrogens
E)
Progesterone
Ans:
B, C, D
Feedback:
Both androgens (testosterone and dihydrotestosterone) and estrogens appear to contribute to the development of BPH. Testosterone is the most important factor for prostatic growth. DHT, the biologically active metabolite of testosterone, is thought to be the ultimate mediator of prostatic hyperplasia, with estrogen serving to sensitize the prostatic tissue to the growth-producing effects of DHT. Glucocorticoids do not play a role in making the prostate gland enlarge.
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