A client is taking a drug that is moderately highly protein bound. Several days later, the client takes a second drug that is 90% protein bound. What is most likely to have occurred as a result of this administration?
a. The first drug remains protein bound.
b. The first drug becomes increasingly inactive.
c. The first drug is released from the protein and becomes more pharmacologically active.
d. The second drug becomes more active.
ANS: C
Only drugs not bound to protein are active and can cause a pharmacologic response. As the free drug in the circulation decreases, more bound drug is released from the protein to maintain the balance of free drug.
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A patient who has been newly diagnosed with adrenal hormone deficiency will begin taking hydrocortisone. The nurse provides teaching for this patient. Which statement by the patient in-dicates understanding of the teaching?
a. "I may take all of my daily dose in the morning or divide it in half and take it twice daily." b. "I will need to take this medication until my symptoms completely clear, and then I may stop." c. "Side effects are common with hydrocor-tisone, even with therapeutic doses." d. "When I am sick, I should take three times the normal dose for 3 days in a row."
A client arrives in the emergency room in the nonprogressive stage of shock. What clinical manifestations would the nurse expect this client to exhibit?
A. Decreased heart rate and decreased urinary output B. Increased heart rate and decreased urinary output C. Increased pulse pressure and increased heart rate D. Decreased pulse pressure and decreased heart rate
A client is prescribed gemfibrozil (Lopid) for treatment of hyperlipidemia type IV. What is important for the nurse to teach the client?
a. "Take aspirin before the medication if you experience facial flushing." b. "You may experience headaches with this medication." c. "You will need to have weekly blood drawn to assess for hyperkalemia." d. "Cholesterol levels will need to be assessed daily for one week."
To break the chain of infection at the reservoir level, the nurse should:
A. Change a soiled dressing B. Keep drainage systems intact C. Cover the nose and mouth when sneezing D. Avoid contact of the uniform with soiled items