A jaundiced 35-year-old white prostitute was evaluated for fatigue. Laboratory results were as
follows
What is the most likely diagnosis?
Complete blood count (CBC)—within normal limits
Urinalysis—2+ bilirubin
Renal function tests (BUN and creatinine)—within normal limits
Liver function tests—liver enzymes and bilirubin elevated
Electrolytes and glucose—within normal limits
Antinuclear antibody (ANA)—positive, speckled pattern
Antimitochondrial antibody—negative
Antismooth muscle antibody—positive
Antineutrophil cytoplasmic antibody (ANCA)—negative
Hepatitis A virus antibody—negative
Hepatitis B surface antigen—negative
Antibody to hepatitis B core antigen—negative
Antibody to hepatitis C antigen—negative
Anti-HIV—negative
A) Systemic lupus erythematosus (SLE)
B) Autoimmune hepatitis
C) Primary sclerosing cholangitis
D) Viral hepatitis
E) Primary biliary cirrhosis
B
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Answer the following statement true (T) or false (F)
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